POTENSI BAHAN HERBAL EKSTRAK ETANOL DAUN MENGKUDU ASAL DESA WAJAK LOR, TULUNGAGUNG, JAWA TIMUR TERHADAP BAKTERI PENYEBAB JERAWAT

  • ELYSABET HERAWATI Universitas Nusantara PGRI Kediri
  • TISA RIZKIKA NUR AMEL Universitas Nusantara PGRI Kediri
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Abstract

ABSTRAK

 

Jerawat (acne vulagris) merupakan gangguan kulit akibat peran bakteri Staphylococcus aureus dan Propionibacterium acnes  yang hampir dialami oleh semua kalangan usia wanita dan pria mulai umur 14-30 tahunan. Penggunaan obat antibiotik justru menunjukkan resiko dan resistensi bakteri. Saat ini penelitian obat herbal semakin berkembang karena efek sampingnya realtif kecil dan lebih aman. Salah satu tanaman yang berpotensi antibakteri adalah mengkudu. Penelitian bertujuan untuk mengetahui potensi ekstrak etanol daun mengkudu asal Desa Wajak Lor, Tulungagung, Jawa Timur terhadap bakteri uji penyebab jerawat yakni Staphylococcus aureus. Proses ekstraksi dilakukan dengan metode maserasi dengan etanol 96%. Uji Kromatografi Lapis Tipis juga dilakukan agar mengetahui kehadiran senyawa antibakteri dalam ekstrak etanol daun mengkudu. Pengujian daya hambat ekstrak etanol daun mengkudu pada Staphylococcus aureus dilakukan dengan metode difusi cakram dengan konsentrasi ekstrak 25%, 50%, 75%, dan 100%. Hasil penelitian menunjukkan bahwa esktrak etanol daun mengkudu konsentrasi 100% menghasilkan zona hambat terbaik dengan rata-rata zona 11,5 mm dan termasuk zona hambat kategori kuat. Berdasarkan hasil penelitian, maka ekstrak etanol daun mengkudu asal Desa Wajak Lor, Tulungagung, Jawa Timur memiliki potensi antibakteri pada bakteri penyebab jerawat Staphylococcus aures.

 

 

Kata Kunci: daun mengkudu, esktrak etanol, bakteri penyebab jerawat

 

 

ABSTRAC

 

Acne (acne vulagris) is a skin disorder due to the role of Staphylococcus aureus and Propionibacterium acnes bacteria which are almost experienced by all ages of women and men from the age of 14-30 years. The use of antibiotic drugs actually shows the risk and resistance of bacteria. At present, the research on herbal medicine is increasing because the side effects are relatively small and safer. One plant that has the potential to be antibacterial is noni (mengkudu). The aim of this study was to determine the potential ethanol extract of noni leaves from Wajak Lor Village, Tulungagung, East Java to against the bacteria that cause acne namely Staphylococcus aureus. The extraction process was carried out by maceration method with 96% ethanol. Thin Layer Chromatography Test was also conducted to determine the presence of antibacterial compounds in the ethanol extract of noni leaves. The inhibitory test of noni extract ethanol extract on Staphylococcus aureus was carried out by disk diffusion method with extract concentrations of 25%, 50%, 75%, and 100%. The results showed that 100% noni concentration of noni leaf extract produced the best inhibition zone with an average zone of 11.5 mm and included a strong inhibition zone. Based on the results of the study, the noni extract of noni leaves from the village of Wajak Lor, Tulungagung, East Java has antibacterial potential in the bacteria that causes acne Staphylococcus aures.

 

 

Keywords: noni leaves, ethanol extract, acne-causing bacteria

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Published
2018-09-19
How to Cite
HERAWATI, E., & NUR AMEL, T. R. (2018). POTENSI BAHAN HERBAL EKSTRAK ETANOL DAUN MENGKUDU ASAL DESA WAJAK LOR, TULUNGAGUNG, JAWA TIMUR TERHADAP BAKTERI PENYEBAB JERAWAT. JuKe (Jurnal Kesehatan), 2(2). Retrieved from https://jurnal.stikesganeshahusada.ac.id/index.php/juke/article/view/122
Issue
Vol. 2 No. 2 (2018)
Section
Research

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